chondroitin for osteoarthritis
4 month ago
Product details
Chondroitin sulfate is an acidic mucopolysaccharide, a macrom extracted from animal cartilage tissue.
1.Sources Extracted from animal tissues It mainly comes from the cartilage of animals such as pigs, cows, sharks. During the extraction process, the cartilage tissue is first washed and ground as preprocessing, then chondroitin sulfate is separated from the extracellular matrix cartilage cells through enzymatic hydrolysis or chemical extraction. For example, in the enzymatic hydrolysis process, specific proteases are used to break the protein components in the cartilage tissue, releasing chondroitin sulfate, which is then purified and separated to obtain high-purity chondroitin sulfate
2. Chemical Properties Acidity and poly-anionic characteristics The chondroitin sulfate molecule contains sulfate groups, giving it acidity. It can ionize ions and negatively charged poly-anionic groups in aqueous solutions. This poly-anionic characteristic allows chondroitin sulfate to interact with cations (such as and magnesium ions) and to electrostatically bind with positively charged biomolecules like proteins. Solubility and viscosity Chondroitin sulfate has good solility in water, and its solution has a certain viscosity. This viscosity property is related to the length of its molecular chain, branching, and solution concentration. Solutions higher concentrations of chondroitin sulfate have higher viscosities, which can be used in applications requiring thickening effects. Stability Chondroitin is stable under normal physiological conditions (such as body temperature and neutral pH environments), but it may degrade under extreme pH values, high temperatures, or high enzyme concentrations For example, in strongly acidic or alkaline environments, the glycosidic bonds in the chondroitin sulfate molecule may break, leading to the destruction its molecular structure.
3. Uses and Applications Medical field Osteoarthritis treatment: Chondroitin sulfate is an important drug component for treatingoarthritis. It can promote the metabolism of cartilage cells, stimulate the synthesis of proteoglycans and collagen by cartilage cells, and help and maintain the normal structure of joint cartilage. When used in combination with glucosamine, it can synergistically improve the symptoms of joint pain, swelling, functional impairment in osteoarthritis patients. Clinical studies have shown that patients who take a combination of chondroitin sulfate and glucosamine for a long have a slower narrowing of their joint spaces and better maintenance of joint function.
Cardiovascular disease treatment: Chondroitin sulfate also has applications in cardiovascular diseases It can lower cholesterol and triglyceride levels in the blood, reducing the risk of atherosclerosis. At the same time, chondroitin sulfate can platelet aggregation, preventing thrombosis and providing protection for the cardiovascular system. It plays a positive role in the treatment of diseases such as coronary heart disease and infarction.
Ophthalmic applications: In the field of ophthalmology, chondroitin sulfate can be used to treat diseases such as corne ulcers and dry eye syndrome. It can form a protective layer on the surface of the cornea, maintaining moisture and promoting the repair of corneal damage Additionally, chondroitin sulfate can improve blood circulation in the eyes, alleviating eye fatigue and other symptoms. Healthcare field Joint health: As a supplement, chondroitin sulfate is widely used for joint health. It provides nutritional support for joint cartilage
Trust in our Pharmaceutical Chemicals, Chinese Herb Extracts, and APIs for high-quality formulations!
1.Sources Extracted from animal tissues It mainly comes from the cartilage of animals such as pigs, cows, sharks. During the extraction process, the cartilage tissue is first washed and ground as preprocessing, then chondroitin sulfate is separated from the extracellular matrix cartilage cells through enzymatic hydrolysis or chemical extraction. For example, in the enzymatic hydrolysis process, specific proteases are used to break the protein components in the cartilage tissue, releasing chondroitin sulfate, which is then purified and separated to obtain high-purity chondroitin sulfate
2. Chemical Properties Acidity and poly-anionic characteristics The chondroitin sulfate molecule contains sulfate groups, giving it acidity. It can ionize ions and negatively charged poly-anionic groups in aqueous solutions. This poly-anionic characteristic allows chondroitin sulfate to interact with cations (such as and magnesium ions) and to electrostatically bind with positively charged biomolecules like proteins. Solubility and viscosity Chondroitin sulfate has good solility in water, and its solution has a certain viscosity. This viscosity property is related to the length of its molecular chain, branching, and solution concentration. Solutions higher concentrations of chondroitin sulfate have higher viscosities, which can be used in applications requiring thickening effects. Stability Chondroitin is stable under normal physiological conditions (such as body temperature and neutral pH environments), but it may degrade under extreme pH values, high temperatures, or high enzyme concentrations For example, in strongly acidic or alkaline environments, the glycosidic bonds in the chondroitin sulfate molecule may break, leading to the destruction its molecular structure.
3. Uses and Applications Medical field Osteoarthritis treatment: Chondroitin sulfate is an important drug component for treatingoarthritis. It can promote the metabolism of cartilage cells, stimulate the synthesis of proteoglycans and collagen by cartilage cells, and help and maintain the normal structure of joint cartilage. When used in combination with glucosamine, it can synergistically improve the symptoms of joint pain, swelling, functional impairment in osteoarthritis patients. Clinical studies have shown that patients who take a combination of chondroitin sulfate and glucosamine for a long have a slower narrowing of their joint spaces and better maintenance of joint function.
Cardiovascular disease treatment: Chondroitin sulfate also has applications in cardiovascular diseases It can lower cholesterol and triglyceride levels in the blood, reducing the risk of atherosclerosis. At the same time, chondroitin sulfate can platelet aggregation, preventing thrombosis and providing protection for the cardiovascular system. It plays a positive role in the treatment of diseases such as coronary heart disease and infarction.
Ophthalmic applications: In the field of ophthalmology, chondroitin sulfate can be used to treat diseases such as corne ulcers and dry eye syndrome. It can form a protective layer on the surface of the cornea, maintaining moisture and promoting the repair of corneal damage Additionally, chondroitin sulfate can improve blood circulation in the eyes, alleviating eye fatigue and other symptoms. Healthcare field Joint health: As a supplement, chondroitin sulfate is widely used for joint health. It provides nutritional support for joint cartilage
Trust in our Pharmaceutical Chemicals, Chinese Herb Extracts, and APIs for high-quality formulations!
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