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Adapalene is a retinoic acid compound

3 year ago
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Adapalene is a retinoic acid compound that has been shown to have anti-inflammatory properties in vivo and in vitro models of inflammation, is chemically stable and does not readily decompose in air and light. The mechanism of action is the same as retinoic acid, which binds to a specific retinoic acid nuclear receptor, except that adapaline does not bind to a protein-bound cytoplasmic receptor. Adapaline has been shown to treat acne in skin trials in an animal model established in mice, and has also been shown to be effective in treating acne vulgaris and in the differentiation process. The mechanism of action is to reduce the formation of microacne by normal differentiation of Chemicalbook hair cells on hair follicles. Standard anti-inflammatory assays in vivo and in vitro. Adapalin is more effective than retinoic acid. It can inhibit the chemotaxis of human multinucleated leukocytes, and inhibit the metabolism of pleomorphic nucleate's hypoplasia by inhibiting the conversion of arachidonic acid to inflammatory mediators through lipid oxidation, thereby alleviating the inflammatory response mediated by cell response. It is suitable for the treatment of acne, pimples and pustules as the main manifestations of common type of skin acne. It can also be used to treat acne on the face, chest and back.
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