What is lincomycin?

Lincomycin is a lincosamide antibiotic produced by Streptomyces lincomycin. Its chemical formula is C18H34N2O6S, its molecular weight is 406.54, and it is white or off-white powder, with a slight or special odor and bitter taste. It is easily soluble in water or methanol and slightly soluble in ethanol. Lincomycin mainly achieves its bactericidal effect by inhibiting the synthesis of bacterial proteins. It acts on the 50S subunit of the ribosome of sensitive bacteria, preventing the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. As an antibiotic, lincomycin is mainly used to treat infectious diseases caused by Gram-positive bacteria. This is pharmaceutical raw materials and a common antibiotic ingredient in medicine.

What are the functions of lincomycin?

1. Antibacterial ingredients: Lincomycin has good antibacterial activity against a variety of Gram-positive bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, etc. These pathogens are widely present in the human body and cause various types of infectious diseases.
2. Anti-inflammatory effect: Lincomycin can reduce the degree of inflammatory response and promote the repair of damaged tissues. This is very important in treating many infectious diseases, such as respiratory tract infections, skin and soft tissue infections, etc.
3. Immunomodulation: However, it is worth noting that long-term use of lincomycin may decrease the body's immunity. Therefore, in some cases, it is necessary to use it in combination with other drugs with immunomodulatory functions to maintain the patient's immune system balance.
4. Analgesic effect: Lincomycin can relieve pain symptoms by affecting the release of neurotransmitters. This effect may help improve the patient's quality of life and reduce the need for other analgesics.
5. Cardiovascular protection: Lincomycin is also considered to have a certain cardiovascular protective effect. It can lower blood pressure, reduce the incidence of myocardial infarction, and has a certain effect on preventing coronary atherosclerosis.

Application:

1. Pharmaceutical Chemicals: Lincomycin is mainly used for various infections caused by sensitive bacteria, such as pneumonia, bronchitis, sepsis, osteomyelitis, cellulitis, suppurative arthritis and mastitis. It can also be used to prevent and treat anaerobic infections, such as chronic respiratory diseases in poultry, panting disease in pigs, necrotic enteritis in chickens, etc.
2. Veterinary Applications: In the veterinary field, lincomycin is also widely used in the treatment and prevention of animal diseases. For example, it can be used to prevent and treat treponemal bloody diarrhea, mycoplasma pneumonia in pigs, air sac inflammation, clostridial necrotic enteritis in chickens, and acute hoof rot in dairy cows.
3. Aquaculture Applications: In aquaculture, lincomycin is also used to prevent and treat diseases in the fry stage.