Puerarin powder

Puerarin is a flavonoid compound extracted from the roots of the leguminous plants Paria lobata or Pueraria thomsonii.

一.   Chemical Structure and Properties The chemical name of puerarin is 4',7-dydroxy-8-β-D-glucopyranosylisoflavone, with a molecular formula of C21H20O9. It a white to pale yellow crystalline powder, soluble in methanol and ethanol, and slightly soluble in water. This compound contains multiple phenolic hydroxyl groups which gives it certain antioxidant activities and the ability to scavenge excessive free radicals in the body.

二.    Pharmacological Effects

1. Antihypertensive ingredients ：Puerarin can inhibit the activity of the renin-angiotensin-aldosterone system (RAAS), reducing the production of angiotensin, thereby causing peripheral vasodilation and lowering blood pressure. At the same time, it can improve vascular endothelial function and regulate the contraction and dilation state of vessels.

2. Anti-arrhythmia: It has a certain improvement effect on various types of arrhythmias, such as ventricular and atrial premature. It mainly works by regulating the ion channels on the myocardial cell membrane, stabilizing the electrical activity of myocardial cells, and reducing the generation of abnormal impulses.

In terms of the cerebral vascular system:

3. Improving cerebral circulation: Puerarin can cross the blood-brain barrier, dilate cerebral blood, and increase cerebral blood flow. This is very important for improving cerebral ischemia and hypoxia, and has certain application value in the treatment of cerebro diseases such as cerebral infarction and transient ischemic attacks. It can also inhibit platelet aggregation, reduce blood viscosity, and decrease the risk of thromb.

 4. Anti-oxidant Raw Material: Due to the phenolic hydroxyl groups in its chemical structure, puerarin has strong antioxidant capabilities. It canavenge superoxide anion radicals, hydroxyl radicals, and other reactive oxygen species in the body, reducing the damage caused by oxidative stress reactions to cells

三. Application Fields

 1. Pharmaceutical raw materials field: Used in the treatment of cardiovascular diseases such as coronary heart disease, angina pectoris, and myocardialarction. In clinical practice, puerarin is often made into an injection, which is administered intravenously to quickly improve the patient's myocardial ischem symptoms.

2. Health products field: As a natural antioxidant and cardiovascular protector, puerarin is widely used in the development of health products. For example, health products with puerarin as the main ingredient claim to improve cardiovascular health and alleviate fatigue. However, the efficacy of health products needs scientific verification and cannot replace for disease treatment.

3.Cosmetics materials : Due to its antioxidant effects, puerarin is added to some cosmetics, such as creams and serums. can help reduce skin oxidation damage, delay skin aging, and reduce the formation of wrinkles. It also has certain anti-inflammatory effects, which can help improve skin inflammation acne.